Pregnancy-relevant infections

Clinical information

The term TORCH encompasses all infectious agents that can be transferred from mother to child in the uterus, during birth or after birth via vertical infection. It includes Toxoplasma gondii, rubella virus, cytomegalovirus (CMV), herpes simplex virus (HSV) and other pathogens such as Chlamydia trachomatis, parvovirus B19, Treponema pallidum and varicella zoster virus (VZV). Primary infections during pregnancy are especially feared, since they are associated with an increased risk of damage to the child.

Diagnostics

Analysis of antibodies against TORCH parameters is an essential part of pre-, peri- and postnatal care. The tests allow the immune status of the mother to be established and the risks to
an existing pregnancy assessed. TORCH tests are generally performed during the first trimester of pregnancy, but they can also be carried out on the newborn if an infection is suspected. The initial investigation of antibodies against TORCH pathogens is aimed at determining the immune status of the mother in order to be able to differentiate between acute primary and past infections or reactivations during the course of pregnancy. If diagnosed early, TORCH infections can in part be effectively treated, reducing the risk of birth defects or loss of the foetus.

Selected Products

MethodParameterSubstrateSpecies 
WESTERNBLOTantibodies against Treponema pallidum
IgG positive control
Details
WESTERNBLOTantibodies against Treponema pallidum
IgM positive control
Details
WESTERNBLOTTreponema pallidumWesternblotDetails
EUROLINETreponema pallidum
(TpN15, TpN17, TmpA, TpN47 separately)
EUROLINEDetails
IIFTTreponema pallidum
(FTA-ABS)
bacterial
smear
verification BIOCHIP
(2 BIOCHIPs per field)
T. pallidumDetails
EUROLINEpositive control serum: IgG, human, 50x concentrated
for Treponema pallidum
Details
EUROLINEpositive control serum: IgM, human, 50x concentrated
for Treponema pallidum
Details
ELISATreponema pallidumantigen-coated
microplate wells
Details
ELISATreponema pallidum
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISATreponema pallidum
Screen ELISA
antigen-coated
microplate wells
Details
WESTERNBLOTEUROLINE-WB
Treponema pallidum
plus cardiolipin
WesternblotDetails
ELISACSQ pair of controls
anti-Treponema pallidum (IgG)
Details
ELISATreponema pallidum
antibody determination in CSF
antigen-coated
microplate wells
Details
IIFTTreponema pallidum
(FTA-ABS)
bacterial
smears
verification BIOCHIP
(3 BIOCHIPs per field)
T. pallidum
T. phagedenis
Details
IIFTChlamydia
trachomatis
infected cellsEU 40Details
ELISAChlamydia trachomatisantigen-coated
microplate wells
Details
ELISAChlamydia trachomatisantigen-coated
microplate wells
Details
ELISAChlamydia trachomatis
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
IIFTAnti-Chlamydia MIF
Chlamydia trachomatis
Chlamydia pneumoniae
Chlamydia psittaci
4 BIOCHIPs per field:
elementary bodies
and non-infected cells

EU 40
EU 40
EU 40
Details
IIFTAnti-Chlamydia MIF EUROPattern
Chlamydia trachomatis
Chlamydia pneumoniae
Chlamydia psittaci
4 BIOCHIPs per field:
elementary bodies
and non-infected cells

EU 40
EU 40
EU 40
Details
IIFTChlamydia trachomatiselementary bodies (MIF)
non-infected cells
(2 BIOCHIPs per field)
EU 40
EU 40
Details
ELISAToxoplasma gondiiantigen-coated
microplate wells
Details
IIFTToxoplasma
gondii
protozoan
smear
Toxoplasma
gondii
Details
ELISAToxoplasma gondii Screenantigen-coated
microplate wells
Details
ELISAToxoplasma gondiiantigen-coated
microplate wells
Details
ELISAToxoplasma gondii
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISAToxoplasma gondii
avidity determination
antigen-coated
microplate wells
Details
EUROLINE"TO.R.C.H. 10"
(Toxoplasma gondii, Rubella virus, CMV,
HSV-1, HSV-2, Bordetella pertussis, Chlamydia trachomatis,
Parvovirus B19, Treponema pallidum, VZV separately)
EUROLINEDetails
EUROLINE"TO.R.C.H. Profile"
(Toxoplasma gondii, ROP1, Rubella virus,
CMV, HSV-1, HSV-2 separately)
EUROLINEDetails
EUROLINE"TO.R.C.H. Profile"
(Toxoplasma gondii, Rubella virus,
CMV, HSV-1, HSV-2 separately)
EUROLINEDetails
EUROLINEpositive control serum: IgG, human, 50x concentrated
for TO.R.C.H. Profile
Details
EUROLINEpositive control serum: IgM, human, 50x concentrated
for TO.R.C.H. Profile
Details
ELISACSQ pair of controls
anti-Toxoplasma gondii (IgG)
Details
ELISAToxoplasma gondii
antibody determination in CSF
antigen-coated
microplate wells
Details
PCREURORealTime HSV-1/2Details
EUROArrayEUROArray HSV1/2 VZVDetails
ChLIAControl set
Herpes simplex virus 1 (HSV-1)
Details
WESTERNBLOTantibodies against Herpes simplex virus (HSV)
IgG positive control
Details
ChLIAHerpes simplex virus 1
(HSV-1)
Details
ELISACSQ pair of controls
anti-HSV-1/2 Pool (IgG)
Details
WESTERNBLOTEUROLINE-WB
Herpes simplex virus 1 (HSV-1)
plus HSV-2 type-specific
glycoprotein G2
WesternblotDetails
ELISAHerpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
Details
ELISAHerpes simplex virus
(HSV-1/2 Pool)
antibody determination in CSF
antigen-coated
microplate wells
Details
ELISAHerpes simplex virus
(HSV-1/2 Pool)
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISAHerpes simplex virus 1
(HSV-1)
antigen-coated
microplate wells
Details
ChLIAHerpes simplex virus 2 (HSV-2)Details
ChLIAControl set
Herpes simplex virus 2 (HSV-2)
Details
ELISAHerpes simplex virus 2
(HSV-2)
antigen-coated
microplate wells
Details
ELISACytomegalovirus
(CMV)
antigen-coated
microplate wells
Details
ELISACytomegalovirus (CMV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISACytomegalovirus (CMV)
avidity determination
antigen-coated
microplate wells
Details
ELISACytomegalovirus (CMV) p52
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISACytomegalovirus
(CMV) gB
antigen-coated
microplate wells
Details
ELISACSQ pair of controls
anti-Cytomegalovirus (IgG)
Details
ELISACytomegalovirus (CMV)
antibody determination in CSF
antigen-coated
microplate wells
Details
EUROLINEParvovirus B19
(VP1, VLP, VP2, NS1 separately)
EUROLINEDetails
ELISAParvovirus
B19
antigen-coated
microplate wells
Details
ELISAParvovirus B19
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
WESTERNBLOTRubella virusWesternblotDetails
IIFTRubella virusinfected cellsEU 13Details
ELISARubella virusantigen-coated
microplate wells
Details
ELISARubella virus
avidity determination
antigen-coated
microplate wells
Details
ELISARubella virus glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISACSQ pair of controls
anti-Rubella virus (IgG)
Details
ELISARubella virus
antibody determination in CSF
antigen-coated
microplate wells
Details
ELISAVaricella zoster virus
(VZV)
antigen-coated
microplate wells
Details
IIFTVaricella zoster virus
(VZV)
infected cellsEU 168Details
ELISAVaricella zoster virus
(VZV)
antigen-coated
microplate wells
Details
ELISAVaricella zoster virus (VZV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISAVaricella zoster virus (VZV)
avidity determination
antigen-coated
microplate wells
Details
ELISAVaricella zoster virus (VZV) glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISACSQ pair of controls
anti-VZV (IgG)
Details
ELISAVaricella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
Details
ELISAVaricella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
Details
IIFTZika virus (ZIKV)infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14Details
IIFTZika virus (ZIKV) EUROPatterninfected and non-
infected cells
(2 BIOCHIPs per field)
EU 14Details
PCREURORealTime Zika VirusDetails
ELISAZika virus (ZIKV)antigen-coated
microplate wells
Details
ELISAZika virus (ZIKV)antigen-coated
microplate wells
Details
ELISAZika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
ELISAZika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
Details
IIFTArbovirus Fever Mosaic 2
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
Details
IIFTArbovirus Fever Mosaic 2 EUROPattern
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
Details
IIFTArbovirus Profile 3
upper row :
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
bottom row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)


infected cells
infected cells
infected cells

infected cells
infected cells
infected cells
infected cells


EU 14
EU 14
EU 14

EU 14
EU 14
EU 14
EU 14
Details